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The acidic environment inhibits the infiltration and antitumor function of natural killer (NK) cells, Dendritic cells (DCs), and CD8 + T cells [73,74,75,76,77]

Figure 9 Analysis of mRNA sequencing results from wild strain TPC-1 cells and RRM2 overexpression strain ( RRM2 -OE-TPC-1) showed significant enrichment of differential genes in the cell cycle pathway, as shown in Supplementary Table 4

Hubbard, J

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